Dopamine is synthesised in the basal ganglia cells in the brain. However, it can no longer be produced if these cells are destroyed. This deficit triggers the symptoms of Parkinson's disease.
From a medical standpoint, Parkinson’s disease manifests in two primary forms:
Primary Parkinson's disease:
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Primary Parkinson's disease occurs when the motor neurons responsible for motor action lack dopamine production. This deficit arises due to the destruction of basal ganglia cells in the brain, triggered by the accumulation of proteins forming Lewy bodies.
Secondary parkinsonism:
Secondary Parkinsonism emerges when dopamine-producing cells malfunction but are not destroyed. This condition often results from viral infections, nervous system diseases, or the use of certain medications like haloperidol.
Over the years, researchers have explored various preventive measures to delay or mitigate the onset of Parkinson’s disease. Some notable hypotheses include:
Unsaturated fatty acids and Omega-3: Consuming unsaturated fatty acids like Omega-3 can bolster neuron membrane protection, potentially thwarting neuron destruction and the onset of Parkinson's disease.
Vitamins: Vitamins D and E exhibit preventive properties against Parkinson's disease, with vitamin E acting as a potent antioxidant to safeguard against neurodegeneration.
Other substances: Moderate consumption of substances like caffeine, nicotine, and ibuprofen is believed to offer protective benefits against Parkinson's disease.
Exercise: Engaging in regular physical activity is recognized for its role in preventing motor disorders associated with Parkinson's disease.
Heavy metals: Avoiding exposure to heavy metals from sources such as food, water, and pollution is crucial, as these elements contribute to nerve cell destruction.
Glucose variations: Sudden fluctuations in glucose absorption by the brain should be minimized to maintain brain health.
Saturated fatty acids: Consumption of saturated fatty acids found in meat and dairy products should be limited to mitigate Parkinson's disease risk.
Alcohol and tobacco: Excessive alcohol consumption and tobacco smoke are detrimental to brain health and exacerbate Parkinson's disease symptoms.
While Parkinson's disease remains incurable, treatments aim to alleviate symptoms until advancements in medical research offer new solutions. As the disease progresses, elderly individuals may require assistance with daily activities, necessitating support from caregivers and specialized care homes.
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